Well-differentiated liposarcoma.

From the axilla. Some people would call this an atypical lipoma. It was excised and recurred locally. It is a very low-grade malignant tumor of adipose tissue, with almost no potential to metastasize. Fat cells are located in the upper right hand corner. The only hint that these are malignant is that they differ markedly in size. But note the large, darkly-stained, irregular shaped nuclei of some of the other cells, which do not exhibit fat vacuoles. This is also evidence of malignancy. You can even see nucleoli in many of these cells, indicating protein production. Elsewhere there were a few lipoblasts, and the tumor was invading skeletal muscle.


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