Basic Histology -- Smooth Muscle vs. Dense Connective Tissue Next Home Back

One important challenge is to distinguish dense connective tissue from smooth muscle.

Remember that smooth muscle will present the features we've just seen, in either longitudinal or transverse cut.

In dense connective tissue, the nuclei will usually be outside the fibers.

Remember that smooth and skeletal muscle "fibers" are cells, while connective tissue "fibers" are cables of acellular collagen.

This is the border of smooth muscle and dense irregular connective tissue.

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Kansas City University of Medicine and Biosciences