Basic Histology -- Lymphocytes and Giant Cells Next Home Back

Macrophages are cells in the tissues that eat debris and certain invaders.

When macrophages travel via the bloodstream, we call them monocytes.

We won't expect you to spot single macrophages in tissue, unless they have eaten a lot of something easy-to-see.

These macrophages have gotten excited about something and have fused to form giant cells. You can recognize them because their nuclei seem to overlap within a mass of cytoplasm. Often the nuclei are arranged in a rim around the edge of the cytoplasm.

This is a cluster including two giant cells.

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Kansas City University of Medicine and Biosciences